女用安全套能杀艾滋病毒?


女用安全套能杀艾滋病毒?

 
 
 
 
 

女用安全套能杀艾滋病毒?
 
( 2009-07-20 )
 
    一种可以供女性自主使用的“杀微生物剂”将发挥和安全套的同等作用,能有效杀死艾滋病病毒,从而减缓艾滋病传播。目前国际上已有产品进入三期临床试验阶段,中国也正在研究中。这是记者11月3日在由世界卫生组织及南京大学公共健康医学中心联合主办的“杀微生物剂在中国的研究和开发”国际研讨会上获得的消息。

    “杀微生物剂其实是一种广谱杀菌剂,可以有效杀死艾滋病毒。但它最大的好处是可由女性自己使用,而不需要依靠伴侣。”清华大学艾滋病综合研究中心常务副主任、中国医学科学院北京协和医学院艾滋病研究中心主任张林琦教授解释说,中国从2006年、2007年开始,性传播已成为艾滋病毒传播的主要途径,我们通常呼吁通过使用安全套来降低传播风险,而杀微生物剂则可以通过女性放入阴道,有效杀死艾滋病病毒和性病病原体。可以预见,杀微生物剂如果和安全套共同使用,艾滋病的传播风险也大大降低。不过目前杀微生物剂的研发面临着一些困难,最关键的技术难点是,既要能杀死艾滋病毒,又不能杀死身体本身存在的有益菌,还不能激活阴道表面细胞,否则反而会加快艾滋病毒感染。南大公共健康医学中心主任吴稚伟是中国从事“杀微生物剂”研究的专家之一,他介绍说,目前国际上有一系列前期产品在研发,有的已进入临床一期、二期和三期,中国也在研究中,不过还没有建立规范的平台,仅在研究所中进行。

    “其实,对艾滋病来说,最关键还是预防,一旦进入体内就无法彻底清除,目前所有药品只能暂时抑制。而且对艾滋病疫苗的研究也非常艰难,可以说至今没什么突破进展。”作为国内研制艾滋病疫苗的权威专家张林琦无奈地说,艾滋病毒进入体内后,与身体的免疫系统会有一个长期的较量过程,最终让免疫系统丧失殆尽。艾滋病毒是病毒中最狡猾的一种,隐蔽性极强,它会进入人体细胞,变成“内奸”,必须把感染病毒的细胞找到,才能有针对性。而当前的疫苗研究感觉有点“乱放箭”,却始终抓不到要害,没有诱导出抗艾滋病毒的有效反应,这也是目前最大的困惑。去年国际上亮相了几百种疫苗,有效的只有三四十种,进入临床三期的只有两种,而且效果还不好。
 
 
作 者:----责任编辑:王海霞 来 源:千龙网

Female condoms can kill HIV?
 
(2009-07-20)
 
     A can be used for women's autonomy, "microbicides" will play the same role, and condoms can effectively kill the AIDS virus, thus slowing the spread of AIDS. At present, there are three products into clinical trials, is studying in China. This is the press on November 3 by the World Health Organization and the University Medical Center, public health, jointly organized the "China microbicide research and development of" an international seminar on access to information.

     "Microbicides is a broad-spectrum fungicides can effectively kill the HIV virus. But it's biggest advantage is their use by women without the need to rely on a partner." Comprehensive AIDS Research Center of Tsinghua University and executive deputy director of China Medical Academy of Sciences, Beijing Union Medical College, director of the Center for AIDS Research Professor Zhang Linqi explained that in 2006 China, in 2007, sexually transmitted HIV transmission has become the main way that we usually call for through the use of condoms to reduce the spread of risk, and microbicides are Add the vagina by women to effectively kill the AIDS virus and sexually transmitted pathogens. It is foreseeable that if the microbicide and the common use of condoms, the spread of AIDS has also greatly reduced the risks. But the current microbicide research and development is faced with some difficulties, the most critical technical difficulty, it is necessary to be able to kill HIV, the body itself can not kill existing bacteria, but also can not activate the surface of cells in the vagina, otherwise it will speed up the AIDS virulence of infection. Public Health South Medical Center, director of Wu Chih-wei of China engaged in "microbicides" study one of the experts, he said, the current series of international pre-products in the R & D, and some have entered clinical Phase I, Phase II and Phase III, China are also being considered, but has yet to develop a standardized platform, only carried out at the Institute.

     "In fact, of AIDS, the most crucial or prevention, as soon as it enters the body can not completely clear, at present only a temporary suppression of all drugs. But also for the AIDS vaccine research is very difficult, no breakthrough can be said that progress so far." As the development of the authority of an AIDS vaccine expert says张林琦, HIV enters the body, the body's immune system and there will be a long-term strength of the process, so that the immune system eventually lost. HIV is a virus, a most cunning, extremely subtle, it will enter the body cells, into a "traitor", the need to find infected cells can be targeted. Vaccine research and the current feeling a bit "chaotic releasing", but always grasp the crucial point, there is no induction of effective anti-HIV response, which is currently the largest confusion. International debut last year, hundreds of types of vaccines, the only valid species三四十, clinical, there are only two of the three, but the effect is not good.
 
 
Editor :---- Author: Wang Haixia Source: Qianlong Network
 
 


 
 

 
 
 
 
 

[ 作者:佚名    转贴自:本站原创    点击数:196    更新时间:2009-7-20    文章录入:nnb ]

 

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