感染HIV的T细胞（红色为HIV病毒，绿色为宿主细胞）。（资料图片）
艾滋病病毒内部结构。（资料图片）
新华网华盛顿６月２１日电 加拿大和美国研究人员２１日发表论文称，他们发现了可能会彻底治愈艾滋病的新方法，艾滋病将有可能不再是不治之症。
治愈艾滋病的关键在于找到艾滋病病毒潜伏池——艾滋病病毒在人体内的藏身之地。研究人员说，他们找到了这种潜伏池，即记忆Ｔ细胞，这是一种人体免疫细胞，尽管它是一些艾滋病病毒的藏身天堂，但也在一定程度上能限制这些病毒的活动。
研究人员发现，一旦艾滋病病毒藏身到记忆Ｔ细胞中，它的命运就与记忆Ｔ细胞休戚相关：细胞活着，病毒也就活着；细胞死亡，病毒也就死亡；病毒增殖也完全依赖于细胞的分裂。因此，摧毁记忆Ｔ细胞，也就可以摧毁“躲藏”起来的艾滋病病毒。
研究人员说，单使用鸡尾酒疗法等抗逆转录病毒疗法治愈不了艾滋病，是因为它对潜伏池内的艾滋病病毒鞭长莫及。于是，他们提出了结合化学疗法和抗逆转录病毒疗法来治疗艾滋病的新方法，其中，抗逆转录病毒疗法可杀灭人体内大部分艾滋病病毒，而化学疗法则专门针对“躲藏”在记忆Ｔ细胞中的艾滋病病毒，这使得艾滋病病毒在人体中再无藏身之地。
这项研究的负责人、蒙特利尔大学的拉菲克－皮埃尔·瑟卡利说，这是首次研究证实，艾滋病之所以治愈不了，不是因为抗逆转录病毒疗法不起效果，而是因为有艾滋病病毒潜伏池的存在。
瑟卡利说，这是初步的研究成果，希望这项成果能指导科学家消灭艾滋病病毒，他们下一步计划在动物身上进行有关试验。
这项研究成果已于２１日发表在英国《自然－医学》杂志上。
Scientists study found that AIDS virus in the human body to hide
June 23, 2009 08:08:42 Source: Xinhua
HIV infection of T cells (red for the HIV virus, green for the host cell). (Picture)
The internal structure of HIV. (Picture)
Xinhua Washington, June 21 Canadian and U.S. researchers published 21 papers said they found a cure for AIDS may be completely new approach to AIDS is likely to be no longer an incurable disease.
The key to cure AIDS is to find latent pool of HIV - HIV in the body of the hide. The researchers said they found a pool of such potential, that is, memory T cells, which is a body's immune cells, although it is hiding some HIV paradise, but also to some extent, to limit the activities of these viruses.
The researchers found that once HIV hiding the memory T cells, which the fate of solidarity and memory T cells: cells alive, the virus is alive; cell death, the virus will be killed; virus proliferation is also totally dependent on cell division . Therefore, the destruction of memory T cells, it can destroy the "hiding" with the AIDS virus.
The researchers said the therapy, such as single-use cocktails of antiretroviral therapy can not cure AIDS, because of its potential pool beyond the reach of the AIDS virus. Thus, their combination with chemotherapy and antiretroviral therapy to treat AIDS, the new method, in which antiretroviral therapy can kill the majority of the human body of HIV, and specific chemotherapy is "hiding" in the memory T HIV cells, which HIV is no longer in the body to hide.
Person in charge of the study, the University of Montreal, Rafiq -瑟卡利Pierre said that this is the first study confirmed that the reason why AIDS can not be cured, not because antiretroviral therapy can not effect, but HIV because of the existence of latent pool.
瑟卡利said that this was the outcome of a preliminary study, we hope that this can guide the outcome of the eradication of HIV scientists, they plan the next step in the test animals.
The results of the study was published in the United Kingdom on the 21st "Nature - Medicine" magazine.
