Infectious disease prevention and control of major national projects - pharmaceutical intervention in immune reconstitution of AIDS research project to start

At 0:01 on July 12, 2009 Source: People's Network

Beijing, July 11 (Xinhua王君平) HIV into the human body, the major violations of the immune system, leading to defects in cellular immunity, resulting in a variety of opportunistic infections and tumors, resulting in the death of the last failure. The status of the immune system and HIV infection is closely related to the formation and development. The state's major infectious diseases prevention and control project - "Chinese medicine intervention on the study of immune reconstitution of AIDS" project to start today in Beijing.

Project Leader of China Academy of Traditional Chinese Medicine Hospital Guang'an Men band Wang said that both before the start of HAART treatment, or treatment, the existence of immune function and prognosis of recovery is the key to the decision. Reconstruction of HIV / AIDS patient's immune function, can make long-term, stable condition, to further improve the efficacy of existing treatments in order to improve HIV / AIDS prognosis of patients.

AIDS-wide known as the acquired immunodeficiency syndrome, the disease by the human immunodeficiency virus infection caused by, resulting in immune function have been infected with the partial or complete loss of, and subsequent multi-system, multi-organ, multi-complex pathogens, such as infections and tumors. As of June 30 this year, China reported a total of HIV infections and 252,748 cases of AIDS patients, of which 73,071 cases of AIDS patients, a total of 48,551 cases of treatment. AIDS has been seriously endanger people's health, and has become a major public health problem and social problems.

At present, including the passive input HIV-specific antibodies or cells, cytokines, such as regulation of the immune phase of immunotherapy being developed, clinical results have not been positive. Immunotherapy ideal drug should be able to function in accordance with timely immune moderate or immune activation play a role in immunosuppression.

Wang bands that AIDS belongs to Chinese medicine, "disease", "V gas blast", "虚劳", "Five injured workers," and so on. In the overall concept of Chinese medicine and syndrome differentiation, under the guidance of clinical research carried out in recent years, in particular, China Academy of Traditional Chinese Medicine in cooperation with Tanzania to carry out a large number of Traditional Chinese Medicine Treatment of attempts in patients with Chinese medicine in improving immune function, improve symptoms, such as to achieve a more good clinical results. Advantage to play a traditional Chinese medicine, the use of methods such as traditional Chinese medicine Fuzheng, research and development with multi-target, two-way regulation of Chinese medicine compound preparation to rebuild the HIV / AIDS patient's immune function, will be the study of Chinese medicine in the fight against AIDS one of the important breakthrough.

Subject to the basis of previous research results, according to the state's major infectious diseases prevention and control projects and project requirements of the relevant provisions of the competent authorities, after a number of professional experts in the field repeatedly argued that the development of a "Chinese medicine intervention on the immune reconstitution of AIDS research," clinical trials program. Modern medicine through clinical and experimental techniques, the use of evidence-based medicine and clinical epidemiology related to modern methods, fully embodied in the concept of Chinese medicine and syndrome differentiation overall premise, the objective evaluation of Chinese medicine intervention on the immune reconstitution of AIDS clinical efficacy and safety of and evidence for the formation for the promotion, widely recognized immune reconstitution of AIDS Chinese medicine provide the basis for comprehensive treatment program.

The subject of the Chinese Academy of Medical Sciences Joint Medicinal Plant Research Institute, Yunnan AIDS Care Center, the People's Liberation Army No. 302 Hospital, Chinese Academy of Medical Sciences Institute of Medicinal Plant, Chinese Academy of Medical Sciences Institute of Laboratory Animal, Beijing Century Pharmaceutical Technology and Culture Development Co., Ltd. A total of six areas of the domestic AIDS research unit, in particular, Bacon Academy Xiao, Zeng Yi, the National Academy of Sciences and other leading experts on the subject of guidance and participation, to achieve a strong joint, and ensuring the authority and nature study.

Wang said order, the project features and innovations include: the project targets the use of laboratory tests and clinical characteristics of combining syndrome differentiation to study AIDS is real or is empty Sheng poisoning syndromes and is conducive to the TCM Syndrome AIDS standardized quantitative diagnosis; strict quality control, integrated traditional Chinese medicine treatment of AIDS patients the impact of immune reconstitution, the use of forward-looking, multi-center randomized, double-blind design, at home and abroad for leading level; of AIDS is false and is true of drug-sheng Syndromes of Molecular Immunology and AIDS-related indicators of research, not been reported in China. In line with international standards of clinical research model, to employ a neutral third party agencies (CRO organization) to carry out project management work, the use of Peking University First Hospital of Medical Statistics of the central room system randomized patients randomized to employ well-known statistics, full participation of experts in evidence-based medicine; the establishment of Chinese medicine treatment of AIDS and to conduct real-time Web site updates, universal access to AIDS prevention and control knowledge, as the majority of patients with online services platform, while promoting academic exchanges, and to speed up the cultivation of innovative talents.